Ms Twinomugisha is a seasoned lawyer. She is a member of the Uganda Law Society, and has served under the Uganda Christian Lawyers Fraternity, East African Law Society and Uganda Federation of Women Lawyers. She also spent 15 years in the Ministry of Defence and Veteran Affairs under various portfolios; first as a prosecutor in the General Court Martial and rose through the ranks to the level of principal legal officer.

Ms Twinomugisha holds a Master of Arts Degree in International Relations and Diplomatic Studies from Makerere University, a Post Graduate Diploma in Legal Practice from the Law Development Centre, a Post Graduate Diploma in Public Administration and Management from Uganda Management Institute and a Bachelor of Laws Degree from Makerere University. She is also credited for the establishment of the Veterans Legal Aid Clinic and creating a supportive mechanism for women’s involvement in peace building.